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DIMT1 Recombinant Protein

Product Specifications

CAS Number

9000-83-3

Gene Name

DIM1 rRNA methyltransferase and ribosome maturation factor

Gene Aliases

18S rRNA (adenine (1779) -N (6) /adenine (1780) -N (6) ) -dimethyltransferase;18S rRNA dimethylase; DIM1; DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1-like; dimethyladenosine transferase; DIMT1 rRNA methyltransferase and ribosome maturation factor; DIMT1L; HSA9761; HUSSY5; probable 18S rRNA (adenine (1779) -N (6) /adenine (1780) -N (6) ) -dimethyltransferase; probable 18S rRNA dimethylase; probable dimethyladenosine transferase; probable S-adenosylmethionine-6-N', N'-adenosyl (rRNA) dimethyltransferase; S-adenosylmethionine-6-N', N'-adenosyl (rRNA) dimethyltransferase.

Gene ID

27292

Accession Number

NP_055288.1

Reactivity

Homo sapiens|Human

Target

Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle (PubMed:25851604) . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604) .

Type

Protein

Source

E.coli

Sequence

MPKVKSGAIGRRRGRQEQRRELKSAGGLMFNTGIGQHILKNPLIINSIIDKAALRPTDVVLEVGPGTGNMTVKLLEKAKKVVACELDPRLVAELHKRVQGTPVASKLQVLVGDVLKTDLPFFDTCVANLPYQISSPFVFKLLLHRPFFRCAILMFQREFALRLVAKPGDKLYCRLSINTQLLARVDHLMKVGKNNFRPPPKVESSVVRIEPKNPPPPINFQEWDGLVRITFVRKNKTLSAAFKSSAVQQLLEKNYRIHCSVHNIIIPEDFSIADKIQQILTSTGFSDKRARSMDIDDFIRLLHGFNAEGIHFS

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid or Lyophilized powder

Buffer

If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Reconstitution

-20°C or -80°C

Molecular Weight

51.2 kDa

Protein Length

Recombinant

NCBI Gene Symbol

DIMT1

Host or Source

Human

Protein Name

Probable dimethyladenosine transferase

Gene Name URL

DIMT1

Nucleotide Accession Number

NM_014473.2

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