HN1 Recombinant Protein
Product Specifications
CAS Number
9000-83-3
Gene Name
Jupiter microtubule associated homolog 1
Gene Aliases
Androgen-regulated protein 2; ARM2; hematological and neurological expressed 1 protein; HN1; HN1A; jupiter microtubule associated homolog 1.
Gene ID
51155
Accession Number
NP_001002032.1
Reactivity
Homo sapiens|Human
Target
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408) . Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422) . Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365) . Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408) .
Type
Protein
Source
E.coli
Sequence
TTTTTFKGVDPNSRNSSRVLRPPGGGSNFSLGFDEPTEQPVRKNKMASNIFGTPEENQASWAKSAGAKSSGGREDLESSGLQRRNSSEASSGDFLDLKGEGDIHENVDTDLPGSLGQSEEKPVPAAPVPSPVAPAPVPSRRNPPGGKSSLVLG
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
-20°C or -80°C
Molecular Weight
31.9 kDa
Protein Length
Recombinant
NCBI Gene Symbol
JPT1
Host or Source
Human
Protein Name
Jupiter microtubule associated homolog 1
Gene Name URL
JPT1
Nucleotide Accession Number
NM_001002032.2
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