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Zosurabalpin (TFA)

Zosurabalpin TFA is a tethered macrocyclic peptide antibiotic, acting specifically on A. baumannii. Zosurabalpin TFA inhibits lipopolysaccharide-transport[1].

Product Specifications

Product Name Alternative

Abx MCP (TFA) ; RG6006 (TFA)

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/zosurabalpin-tfa.html

Solubility

10 mM in DMSO

Smiles

O=C1NCC2=C(C3=CC=C(C=C3)C(O)=O)C=CC=C2SC4=NC=CC=C4CN[C@H](C(N[C@H](C(N([C@H]1CC5=CNC6=CC=CC=C56)C)=O)CCCCN)=O)CCCN.OC(C(F)(F)F)=O.[x]

Molecular Formula

C43H50N8O5S.xC2HF3O2

Molecular Weight

790.97 (free base)

References & Citations

[1]Karanbir S Pahil, et al. A new antibiotic traps lipopolysaccharide in its intermembrane transporter. Nature. 2024 Jan;625 (7995) :572-577.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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