BRD50837

BRD50837 is a potent inhibitor of Sonic Hedgehog (Shh), with the EC50 of 0.09 μM. BRD50837 plays an important role in cancer research[1].

Product Specifications

CAS Number

[1314295-24-3]

UNSPSC

12352005

Target

Hedgehog

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd50837.html

Smiles

O=C(C1CC1)NC2=C(O[C@@H](CN(S(=O)(C3=CC=C(Cl)C=C3)=O)C)[C@@H](C)CN([C@H](C)CO)C4=O)C4=CC=C2

Molecular Formula

C26H32ClN3O6S

Molecular Weight

550.07

References & Citations

[1]Taikangxiang Yun, et al. Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway. Front Chem. 2020 Jun 16:8:498. |[2]Taikangxiang Yun, et al. Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway. Front Chem. 2020 Jun 16:8:498.