BRD50837
BRD50837 is a potent inhibitor of Sonic Hedgehog (Shh), with the EC50 of 0.09 μM. BRD50837 plays an important role in cancer research[1].
Product Specifications
CAS Number
[1314295-24-3]
UNSPSC
12352005
Target
Hedgehog
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd50837.html
Smiles
O=C(C1CC1)NC2=C(O[C@@H](CN(S(=O)(C3=CC=C(Cl)C=C3)=O)C)[C@@H](C)CN([C@H](C)CO)C4=O)C4=CC=C2
Molecular Formula
C26H32ClN3O6S
Molecular Weight
550.07
References & Citations
[1]Taikangxiang Yun, et al. Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway. Front Chem. 2020 Jun 16:8:498. |[2]Taikangxiang Yun, et al. Discovery of Small-Molecule Modulators of the Sonic Hedgehog Pathway. Front Chem. 2020 Jun 16:8:498.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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