Mitochondrial fusion promoter M1

Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury[1][2][3].

Product Specifications

CAS Number

[219315-22-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/mitochondrial-fusion-promoter-m1.html

Purity

99.95

Solubility

DMSO : 38.89 mg/mL (ultrasonic)

Smiles

C/C(C1=CC(Cl)=CC=C1O)=N\NC2=C(Cl)C=C(Cl)C=C2Cl

Molecular Formula

C14H10Cl4N2O

Molecular Weight

364.05

Precautions

H302, H315, H319, H335

References & Citations

[1]Surinkaew P, et, al. Mitochondrial Fusion Promoter Alleviates Brain Damage in Rats with Cardiac Ischemia/Reperfusion Injury. J Alzheimers Dis. 2020;77 (3) :993-1003.|[2]Wang D, et, al. A small molecule promotes mitochondrial fusion in mammalian cells. Angew Chem Int Ed Engl. 2012 Sep 10;51 (37) :9302-5.|[3]Asalla S, et, al. Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells. Sci Rep. 2016 Jun 10;6:27513.