PDGFRα/β/VEGFR-2-IN-1
PDGFRα/β/VEGFR-2-IN-1 (6f), a multiple PDGFRα/ and VEGFR-2 tyrosine kinase inhibitor, particularly targets PDGFRα, PDGFRβ, and VEGFR-2 kinases with Nano molar concentrations[1].
Product Specifications
UNSPSC
12352005
Target
PDGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pdgfrα-β-vegfr-2-in-1.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC=C(NC(COC2=CC=C(/C=C3C(NC4=C\3C=C(Cl)C=C4)=O)C=C2)=O)C=C1
Molecular Formula
C23H16BrClN2O3
Molecular Weight
483.74
References & Citations
[1]Hend A A Ezelarab, et al. New 2-oxoindole derivatives as multiple PDGFRα/ß and VEGFR-2 tyrosine kinase inhibitors. Bioorg Chem. 2024 Apr:145:107234.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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