SPDP-C6-NHS ester
SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[158913-22-5]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/spdp-c6-nhs-ester.html
Purity
98.09
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(CCCCCNC(CCSSC1=NC=CC=C1)=O)ON2C(CCC2=O)=O
Molecular Formula
C18H23N3O5S2
Molecular Weight
425.52
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Curated Selection
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