9-OAHSA
9-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs) . 9-OAHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression. 9-OAHSA is also a protective molecule to prevent colon carcinoma cells from apoptotic cell death[1][2][3].
Product Specifications
CAS Number
154086-90-5
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/9-oahsa.html
Concentration
17.70 mM * 100 μL in Methyl acetate
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/C=C\CCCCCCCC(OC(CCCCCCCC(O)=O)CCCCCCCCC)=O
Molecular Formula
C36H68O4
Molecular Weight
564.92
References & Citations
[1]Zhu QF, et al. Highly sensitive determination of fatty acid esters of hydroxyl fatty acids by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:34-40.2. |[2]Ding J, et al. In-Silico-Generated Library for Sensitive Detection of 2-Dimethylaminoethylamine Derivatized FAHFA Lipids Using High-Resolution Tandem Mass Spectrometry. Anal Chem. 2020 Apr 21;92 (8) :5960-5968.|[3]Li L, et al. Fatty acid esters of hydroxy fatty acids: A potential treatment for obesity-related diseases. Obes Rev. 2024 Mar 10:e13735.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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