9-OAHSA

9-OAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs) . 9-OAHSA shows anti-inflammatory effects via inhibiting cytokine production and reduces IL-1β and IL-6 expression. 9-OAHSA is also a protective molecule to prevent colon carcinoma cells from apoptotic cell death[1][2][3].

Product Specifications

CAS Number

[154086-90-5]

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/9-oahsa.html

Concentration

17.70 mM * 100 μL in Methyl acetate

Purity

99.0

Solubility

10 mM in DMSO

Smiles

CCCCCCCC/C=C\CCCCCCCC(OC(CCCCCCCC(O)=O)CCCCCCCCC)=O

Molecular Formula

C36H68O4

Molecular Weight

564.92

References & Citations

[1]Zhu QF, et al. Highly sensitive determination of fatty acid esters of hydroxyl fatty acids by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:34-40.2. |[2]Ding J, et al. In-Silico-Generated Library for Sensitive Detection of 2-Dimethylaminoethylamine Derivatized FAHFA Lipids Using High-Resolution Tandem Mass Spectrometry. Anal Chem. 2020 Apr 21;92 (8) :5960-5968.|[3]Li L, et al. Fatty acid esters of hydroxy fatty acids: A potential treatment for obesity-related diseases. Obes Rev. 2024 Mar 10:e13735.