Glabridin
Glabridin is a natural isoflavan from Glycyrrhiza glabra L., binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2].
Product Specifications
CAS Number
59870-68-7
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Bacterial; PPAR; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Glabridin.html
Purity
99.98
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
OC1=CC=C([C@H]2CC3=CC=C4C(C=CC(C)(C)O4)=C3OC2)C(O)=C1
Molecular Formula
C20H20O4
Molecular Weight
324.37
Precautions
H302+H312+H332
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARγ
Available Sizes
Frequently Asked Questions
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