N-Acetyl-5-hydroxytryptamine
N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.
Product Specifications
CAS Number
[1210-83-9]
Product Name Alternative
N-Acetylserotonin; Normelatonin; O-Demethylmelatonin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Trk Receptor
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/N-Acetyl-5-hydroxytryptamine.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(NCCC1=CNC2=C1C=C(O)C=C2)=O
Molecular Formula
C12H14N2O2
Molecular Weight
218.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Jang SW, et al. N-acetylserotonin activates TrkB receptor in a circadian rhythm. Proc Natl Acad Sci U S A. 2010 Feb 23;107 (8) :3876-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; TrkB
Available Sizes
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