Anti-Perforin Antibody
Perforin, a pore-forming protein found in the granules of cytotoxic T-lymphocytes and natural killer cells, functions to enable granzymes to enter the target cells and activate apoptosis. It has been suggested that perforin plays a role in alloimmunity, being involved in both the cytolytic process of rejection as well as downregulation of the T-cell mediated responses associated with the alloimmune response. Perforin-mediated cytotoxicity has also been linked to a number of autoimmune diseases.
Product Specifications
Reactivity
Human
Immunogen
Recombinant Protein
Clonality
Monoclonal
Clone
BKJE868
Conjugation
Unconjugated
Purification
Purified
Purity
Purified
Form
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
1:50-1:200
Tested Applications
ELISA, IHC
Host or Source
Mouse
Preservative
Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
Isotype
IgG2c
Frequently Asked Questions
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