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Enrofloxacin (monohydrochloride)

Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV) .

Product Specifications

CAS Number

[93106-59-3]

Product Name Alternative

BAY Vp 2674 (monohydrochloride) ; PD160788 (monohydrochloride)

UNSPSC

12352005

Target

Antibiotic; Bacterial; Endogenous Metabolite; Orthopoxvirus

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/enrofloxacin-monohydrochloride.html

Purity

99.73

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 7.14 mg/mL (ultrasonic)

Smiles

O=C(C1=CN(C2CC2)C3=C(C=C(F)C(N4CCN(CC)CC4)=C3)C1=O)O.[H]Cl

Molecular Formula

C19H23ClFN3O3

Molecular Weight

395.86

References & Citations

[1]Sulyok KM, et al.Antibiotic susceptibility profiles of Mycoplasma bovis strains isolated from cattle in Hungary, Central Europe. BMC Vet Res. 2014 Oct 25;10:256.|[2]Hetze S, et al. Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach. J Cereb Blood Flow Metab. 2013 Jun;33 (6) :846-54.|[3]S Ikeda , et al. Antiviral activity and inhibition of topoisomerase by ofloxacin, a new quinolone derivative. Antiviral Res. 1987 Oct;8 (3) :103-13.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Quinolone

Citation 01

Aquaculture. 30 January 2022, 737541.|Chemosphere. 2023 Nov:340:139892.|Phys Chem Res. 2021 9 (2) : 327-344.|Adv Sci (Weinh) . 2024 Nov 2:e2406766.|bioRxiv. 2024 Nov 06.|Cell Rep. 2023 Mar 21;42 (4) :112290.|Cell Rep. 2024 Feb 17;43 (2) :113804.|Chemosphere. 2019 Jun:225:378-387.|Curr Biol. 2024 May 21:S0960-9822 (24) 00603-1.|Microbiol Spectr. 2025 May 19:e0307424.|Microorganisms. 2025 Apr 18;13 (4) :938.|Neuron. 2021 Aug 18;109 (16) :2573-2589.e9.|Neuron. 2025 Oct 10:S0896-6273 (25) 00706-8.|Vet Microbiol. 2024 May:292:110046.|Virulence. 2025 Dec;16 (1) :2595767.

Available Sizes

Curated Selection

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