1O14

1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes[1].

Product Specifications

UNSPSC

12352200

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1o14.html

Concentration

19.78 mM * 40 μL in Ethanol

Purity

99.0

Smiles

CCCCCCCCCCCCC(CN(CCCN(CC(O)CCCCCCCCCCCC)CCCCNCCCN(CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)CC(O)CCCCCCCCCCCC)O

Molecular Formula

C80H166N4O5

Molecular Weight

1264.20

References & Citations

[1]Schlich, et al. "Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles." Bioengineering & Translational Medicine 6.2 (2021) : e10213.