(S,R,S)-AHPC-C10-NHBoc
Product Specifications
UNSPSC Description
(S,R,S)-AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC (HY-125845) based VHL ligand and a linker used for BET-Targeted PROTAC[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-c10-nhboc.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
Molecular Weight
713.97
References & Citations
[1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2020 Jan 7;15(1):17-25.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148406/S-R-S-AHPC-C10-NHBoc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148406/S-R-S-AHPC-C10-NHBoc-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2412055-13-9
Available Sizes
Curated Selection
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