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(S, R, S) -AHPC-C10-NHBoc

(S, R, S) -AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S) -AHPC (HY-125845) based VHL ligand and a linker used for BET-Targeted PROTAC[1].

Product Specifications

CAS Number

[2412055-13-9]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/s-r-s-ahpc-c10-nhboc.html

Purity

98.32

Solubility

10 mM in DMSO

Smiles

CC(C)(C)OC(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O

Molecular Formula

C38H59N5O6S

Molecular Weight

713.97

References & Citations

[1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2020 Jan 7;15 (1) :17-25.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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