(S, R, S) -AHPC-C10-NHBoc
(S, R, S) -AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S, R, S) -AHPC (HY-125845) based VHL ligand and a linker used for BET-Targeted PROTAC[1].
Product Specifications
CAS Number
[2412055-13-9]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/s-r-s-ahpc-c10-nhboc.html
Purity
98.32
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(NCCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)=O)=O)=O
Molecular Formula
C38H59N5O6S
Molecular Weight
713.97
References & Citations
[1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2020 Jan 7;15 (1) :17-25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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