Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ATM Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

ATM serine/threonine kinase

Gene Aliases

AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1

Gene ID

472

Accession Number

NP_000042.3

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of ATM

Target

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

Clonality

Monoclonal

Type

Monoclonal Antibody

Applications

IHC

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Fragment

IgG1

Specificity

ATM Mouse Monoclonal Antibody (1D1) detects endogenous levels of ATM

NCBI Gene Symbol

ATM

Host or Source

Mouse

Protein Name

Serine-protein kinase ATM

Gene Name URL

ATM

Nucleotide Accession Number

NM_000051.3

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

DAAM2 Polyclonal Antibody
orb618123-01 50 μL

DAAM2 Polyclonal Antibody

Sign In for Pricing
View Details
DAAM2 Polyclonal Antibody
orb618123-02 100 µL

DAAM2 Polyclonal Antibody

Sign In for Pricing
View Details
Phospho-Tau (Ser404) Antibody / MAPT
FY12083 100 µL

Phospho-Tau (Ser404) Antibody / MAPT

Sign In for Pricing
View Details
Trichloroacetonitrile
CS-T-44984 1 Each

Trichloroacetonitrile

Sign In for Pricing
View Details
5-Chloro-6-[ (3,4-difluorophenyl) amino]pyridine-3-carboxylic acid
UQB46614-01 50 mg

5-Chloro-6-[ (3,4-difluorophenyl) amino]pyridine-3-carboxylic acid

Sign In for Pricing
View Details
5-Chloro-6-[ (3,4-difluorophenyl) amino]pyridine-3-carboxylic acid
UQB46614-02 0.5 g

5-Chloro-6-[ (3,4-difluorophenyl) amino]pyridine-3-carboxylic acid

Sign In for Pricing
View Details