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HDAC1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Histone deacetylase 1

Gene Aliases

HD1, RPD3, KDAC1, GON-10, RPD3L1

Gene ID

3065

Accession Number

NP_004955.2

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic Peptide of HDAC1

Target

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Clonality

Monoclonal

Type

Monoclonal Antibody

Applications

IHC

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Fragment

IgG1

Specificity

HDAC1 Mouse Monoclonal Antibody (4E1) detects endogenous levels of HDAC1

NCBI Gene Symbol

HDAC1

Host or Source

Mouse

Protein Name

Histone deacetylase 1

Gene Name URL

HDAC1

Nucleotide Accession Number

NM_004964.2

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