TOMM20 Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

Translocase of outer mitochondrial membrane 20 homolog (yeast)

Gene Aliases

MAS20, MOM19, TOM20

Gene ID

9804

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived between 30-110 amino acids from the Internal region of human Tom20.

Target

Tom20 is a protein encoded by the TOMM20 gene which is approximately 16,2 kDa. Tom20 is localised to the mitochondrion outer membrane and is involved in deubiquitination, metabolism of proteins, pink/parkin mediated mitophagy, and glucose / energy metabolism. It is a central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Tom20 is expressed in the nervous system, bone marrow, pancreas, eye and liver. Mutations in the TOMM20 gene result in Perry syndrome and infantile neuroaxonal dystrophy. STJ96061 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Tom20 protein.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol