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RPS6KA1 Antibody (Phospho-Ser380)

Product Specifications

CAS Number

9007-83-4

Gene Name

Ribosomal protein S6 kinase, 90kDa, polypeptide 1

Gene Aliases

RSK, HU-1, RSK1, p90Rsk, MAPKAPK1, MAPKAPK1A

Gene ID

6195; 81771

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Rsk-1 around the phosphorylation site of S380. Location: 320-400aa.

Target

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

83 kDa

Fragment

IgG

Specificity

Phospho-Rsk-1 (S380) Polyclonal Antibody detects endogenous levels of Rsk-1 protein only when phosphorylated at S380.

NCBI Gene Symbol

RPS6KA1

Host or Source

Rabbit

Gene Name URL

RPS6KA1

Frequently Asked Questions

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