4-Thiazolecarboxylic acid
NCATS-SM1441 (compound 52) is a lactate dehydrogenase (LDH) inhibitor (IC50=40 nM). By inhibiting the activity of LDH, NCATS-SM1441 is able to reduce the production of lactic acid in cancer cells, helping to slow or stop the proliferation of cancer cells.
Product Specifications
CAS Number
1964517-04-1
Product Name Alternative
2-(5-(cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-3-(3-((5-methylthiophen-2-yl)ethynyl)phenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid
Field of Research
Biochemical Reagent Signaling pathways
Purity
0.98
Solubility
Soluble in DMSO
Smiles
FC1=CC(CC2=C(CC3CC3)N(C4=NC(C(O)=O)=CS4)N=C2C5=CC(C#CC6=CC=C(C)S6)=CC=C5)=CC=C1S(N)(=O)=O
Molecular Formula
C31H25FN4O4S3
Molecular Weight
632.74
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.
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