Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

BRAF Antibody (Phospho-Thr599)

Product Specifications

CAS Number

9007-83-4

Gene Name

B-Raf proto-oncogene, serine/threonine kinase

Gene Aliases

NS7, B-raf, BRAF1, RAFB1, B-RAF1

Gene ID

673; 109880

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Raf-B around the phosphorylation site of T599. Location: 540-620aa.

Target

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

85 kDa

Fragment

IgG

Specificity

Phospho-Raf-B (T599) Polyclonal Antibody detects endogenous levels of Raf-B protein only when phosphorylated at T599.

NCBI Gene Symbol

BRAF

Host or Source

Rabbit

Gene Name URL

BRAF

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Sex Hormone Binding Globulin (SHBG) Mouse Monoclonal Antibody [Clone ID: OTI1D10]
TA507136 100 µL

Sex Hormone Binding Globulin (SHBG) Mouse Monoclonal Antibody [Clone ID: OTI1D10]

Sign In for Pricing
View Details
MIND-4
M12482-01 1 g

MIND-4

Sign In for Pricing
View Details
MIND-4
M12482-02 200 mg

MIND-4

Sign In for Pricing
View Details
MIND-4
M12482-03 500 mg

MIND-4

Sign In for Pricing
View Details
MIND-4
M12482-04 5 mg

MIND-4

Sign In for Pricing
View Details
MIND-4
M12482-05 50 mg

MIND-4

Sign In for Pricing
View Details