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PAK1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

P21 protein (Cdc42/Rac) -activated kinase 1

Gene Aliases

IDDMSSD, p65-PAK, PAKalpha, alpha-PAK

Gene ID

5058; 5062; 5063; 224105; 18481; 29431; 100910732; 29433

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human PAK Alpha/Beta/Gamma around the non-phosphorylation site of T423/402/421. Location: 360-440aa.

Target

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

62 kDa

Fragment

IgG

Specificity

PAK Alpha/Beta/Gamma Polyclonal Antibody detects endogenous levels of PAK Alpha/Beta/Gamma protein.

NCBI Gene Symbol

LOC100910732, PAK1, PAK2, PAK3

Host or Source

Rabbit

Gene Name URL

LOC100910732PAK1PAK2PAK3

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