CDK5R1 Antibody - N-terminal region
Product Specifications
CAS Number
9007-83-4
Gene Name
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)
Gene Aliases
P23, p25, p35, CDK5R, NCK5A, CDK5P35, p35nck5a
Gene ID
8851
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived between 30-110 aa from the N-terminal region of human p35.
Target
P35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
IF, IHC, WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight
35 kDa
Fragment
IgG
Specificity
P35 Polyclonal Antibody detects endogenous levels of p35 protein.
NCBI Gene Symbol
CDK5R1
Host or Source
Rabbit
Gene Name URL
CDK5R1
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV766361 1.0 µg DNA
KRT18P42 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
131339-ML650 100 µL
PIK3C2G (Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit gamma, Phosphoinositide 3-kinase-C2-gamma, PI3K-C2gamma, PI3K-C2-gamma, PIK3C2G, PtdIns-3-kinase C2 Subunit gamma, MGC163149) (MaxLight 650)
Sign In for Pricing
View Details 125575 100 µg
CYP2A7 (Cytochrome P450 2A7, CYPIIA7, Cytochrome P450 IIA4)
Sign In for Pricing
View Details