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NFATC1 Antibody (Phospho-Ser294)

Product Specifications

CAS Number

9007-83-4

Gene Name

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

Gene Aliases

NFAT2, NFATc, NF-ATC, NF-ATc1.2

Gene ID

4772

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived between 230-310aa from human NFATc1 around the phosphorylation site of S294.

Target

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells . Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

IHC, WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid.// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20° C. Avoid repeated freeze/thaw cycles.

Molecular Weight

105 kDa

Fragment

IgG

Specificity

Phospho-NFATc1 (S294) Polyclonal Antibody detects endogenous levels of NFATc1 protein only when phosphorylated at S294.

NCBI Gene Symbol

NFATC1

Host or Source

Rabbit

Gene Name URL

NFATC1

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