JAK3 Antibody (Phospho-Tyr785)
Product Specifications
CAS Number
9007-83-4
Gene Name
Janus kinase 3
Gene Aliases
JAKL, LJAK, JAK-3, L-JAK, JAK3_HUMAN
Gene ID
3718; 16453
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human JAK3 around the phosphorylation site of Y785. Location: 720-800aa.
Target
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid//PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
125 kDa
Fragment
IgG
Specificity
Phospho-JAK3 (Tyr785) Polyclonal Antibody detects endogenous levels of JAK3 protein only when phosphorylated at Y785.
NCBI Gene Symbol
JAK3
Host or Source
Rabbit
Gene Name URL
JAK3
Frequently Asked Questions
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