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ITPR1 Antibody (Phospho-Ser1764)

Product Specifications

CAS Number

9007-83-4

Gene Name

Inositol 1,4,5-trisphosphate receptor, type 1

Gene Aliases

ACV, CLA4, IP3R, IP3R1, SCA15, SCA16, SCA29, INSP3R1, PPP1R94

Gene ID

3708; 16438; 25262

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human IP3R-I around the phosphorylation site of S1764. Location: 1700-1780aa.

Target

This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

314 kDa

Fragment

IgG

Specificity

Phospho-IP3R-I (S1764) Polyclonal Antibody detects endogenous levels of IP3R-I protein only when phosphorylated at S1764.

NCBI Gene Symbol

ITPR1

Host or Source

Rabbit

Gene Name URL

ITPR1

Frequently Asked Questions

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