Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

IL10RA Antibody (Phospho-Tyr496)

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin 10 receptor, alpha

Gene Aliases

CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1

Gene ID

3587

Reactivity

Human

Immunogen

Synthesized peptide derived from human IL-10R Alpha around the phosphorylation site of Y496. Location: 440-520aa.

Target

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

63 kDa

Fragment

IgG

Specificity

Phospho-IL-10R Alpha (Tyr496) Polyclonal Antibody detects endogenous levels of IL-10R Alpha protein only when phosphorylated at Y496.

NCBI Gene Symbol

IL10RA

Host or Source

Rabbit

Gene Name URL

IL10RA

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Neuronal nuclei
HAR310-6ml 6 mL

Neuronal nuclei

Sign In for Pricing
View Details
Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)
orb2987051-01 30 µL

Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)

Sign In for Pricing
View Details
Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)
orb2987051-02 100 µL

Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)

Sign In for Pricing
View Details
Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)
orb2987051-03 200 µL

Mouse Anti-GST-tag Antibody Antibody (AcalephFluor488)

Sign In for Pricing
View Details
Zdhhc3 3'UTR Luciferase Stable Cell Line
TU223630 1.0 mL

Zdhhc3 3'UTR Luciferase Stable Cell Line

Sign In for Pricing
View Details
Hepassocin Lentiviral Activation Particles (h)
sc-409612-LAC 200 µL

Hepassocin Lentiviral Activation Particles (h)

Sign In for Pricing
View Details