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IKBKB Antibody (Phospho-Tyr188)

Product Specifications

CAS Number

9007-83-4

Gene Name

Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta

Gene Aliases

IKK2, IKKB, IMD15, IMD15A, IMD15B, NFKBIKB, IKK-beta

Gene ID

3551; 16150; 84351

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Synthesized peptide derived from human IKKBeta around the phosphorylation site of Y188. Location: 130-210aa.

Target

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

86 kDa

Fragment

IgG

Specificity

Phospho-IKKBeta (Tyr188) Polyclonal Antibody detects endogenous levels of IKKBeta protein only when phosphorylated at Y188.

NCBI Gene Symbol

IKBKB

Host or Source

Rabbit

Gene Name URL

IKBKB

Frequently Asked Questions

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