FFAR4 Antibody - middle region
Product Specifications
CAS Number
9007-83-4
Gene Name
Free fatty acid receptor 4
Gene Aliases
GT01, PGR4, BMIQ10, GPR120, GPR129, O3FAR1
Gene ID
338557; 107221; 294075
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human GPR120. Location: 190-270aa.
Target
Receptor for medium and long-chain free fatty acids (FFAs) . Signals via a G (q) /G (11) -coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2) /TAB1-dependent effect, but independent of the G (q) /G (11) -coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
38 kDa
Fragment
IgG
Specificity
GPR120 Polyclonal Antibody detects endogenous levels of GPR120 protein.
NCBI Gene Symbol
FFAR4
Host or Source
Rabbit
Gene Name URL
FFAR4
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