What is the catalog number for DCC Antibody - middle region?

The catalog number for DCC Antibody - middle region is OASG02098-100UL.

What sizes are available for DCC Antibody - middle region?

DCC Antibody - middle region is available in the following size(s): 100 µL.

Is DCC Antibody - middle region in stock?

DCC Antibody - middle region is currently made to order / not held in immediate stock. Contact us for lead time.

DCC Antibody - middle region

Product Specifications

CAS Number

9007-83-4

Gene Name

DCC netrin 1 receptor

Gene Aliases

CRC18, CRCR1, MRMV1, HGPPS2, IGDCC1, NTN1R1

Gene ID

1630; 13176; 25311

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human DCC. Location: 410-490aa.

Target

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol