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KRT2 Antibody (Acetyl-Lys194)

Product Specifications

CAS Number

9007-83-4

Gene Name

Keratin 2, type II

Gene Aliases

K2e, KRTE, CK-2e, KRT2A, KRT2E

Gene ID

3849; 51350; 3850; 3852; 3853; 3854; 286887; 112802; 140807; 319101; 121391; 9119; 338785; 3856; 3890; 16681; 77055; 110308; 406228; 369017

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human Cytokeratin around the acetylation site of K194.

Target

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

65 kDa

Fragment

IgG

Specificity

Acetyl-Cytokeratin-pan (K194) Polyclonal Antibody detects endogenous levels of Cytokeratin protein only when acetylated at K194.

NCBI Gene Symbol

KRT2, KRT3, KRT5, KRT6A, KRT6B, KRT6C, KRT71, KRT72, KRT73, KRT74, KRT75, KRT76, KRT79, KRT8, KRT84

Host or Source

Rabbit

Gene Name URL

KRT2KRT3KRT5KRT6AKRT6BKRT6CKRT71KRT72KRT73KRT74KRT75KRT76KRT79KRT8KRT84

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