XPO1 Antibody (Acetyl-Lys568)

Product Specifications

Gene Name

Exportin 1

Gene Aliases

Emb, CRM1, exp1, CRM-1

Gene ID

7514; 103573; 85252

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from the Internal region of human CRM1 around the acetylation site of K568.

Target

This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES) -dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Fragment

IgG

Specificity

Acetyl-CRM1 (K568) Polyclonal Antibody detects endogenous levels of CRM1 protein only when non-acetylation at K568.

NCBI Gene Symbol

XPO1

Host or Source

Rabbit

Gene Name URL

XPO1

CAS Number

9007-83-4

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