Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CHEK1 Antibody (Phospho-Ser296)

Product Specifications

CAS Number

9007-83-4

Gene Name

Checkpoint kinase 1

Gene Aliases

CHK1

Gene ID

1111

Reactivity

Human

Immunogen

Synthesized peptide derived from human Chk1 around the phosphorylation site of S296. Location: 240-320aa.

Target

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

45 kDa

Fragment

IgG

Specificity

Phospho-Chk1 (S296) Polyclonal Antibody detects endogenous levels of Chk1 protein only when phosphorylated at S296.

NCBI Gene Symbol

CHEK1

Host or Source

Rabbit

Gene Name URL

CHEK1

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal SLC38A4 Antibody [PerCP]
NBP2-81807PCP 0.1 mL

Rabbit Polyclonal SLC38A4 Antibody [PerCP]

Sign In for Pricing
View Details
TAB1, Human (His)
HY-P701639 1 Each

TAB1, Human (His)

Sign In for Pricing
View Details
Herc1 siRNA (m)
sc-145943 10 µM

Herc1 siRNA (m)

Sign In for Pricing
View Details
Bag Heat Seal 180 x 380 x 95mm
AUT1448 500 / PCK

Bag Heat Seal 180 x 380 x 95mm

Sign In for Pricing
View Details
Rabbit Monoclonal OCT4 Antibody (OCT4/6847R) [DyLight 755]
NBP3-21058IR 0.1 mL

Rabbit Monoclonal OCT4 Antibody (OCT4/6847R) [DyLight 755]

Sign In for Pricing
View Details
MYH6 Rabbit Polyclonal Antibody (FITC)
orb189463 100 µL

MYH6 Rabbit Polyclonal Antibody (FITC)

Sign In for Pricing
View Details