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CAMK2B Antibody (Phospho-Thr305)

Product Specifications

CAS Number

9007-83-4

Gene Name

Calcium/calmodulin-dependent protein kinase II beta

Gene Aliases

CAM2, CAMK2, CAMKB, MRD54, CaMKIIbeta

Gene ID

816; 817; 12322; 12323; 108058; 25400; 24245; 24246

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human CaMKII Alpha/Beta/Delta around the phosphorylation site of T305. Location: 240-320aa.

Target

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Reconstitution

Store at -20C. Avoid repeated freeze/thaw cycles.

Molecular Weight

54 kDa

Fragment

IgG

Specificity

Phospho-CaMKII Alpha/Beta/Sigma (T305) Polyclonal Antibody detects endogenous levels of CaMKII Alpha/Beta/Sigma protein only when phosphorylated at T305.

NCBI Gene Symbol

CAMK2A, CAMK2B, CAMK2D

Host or Source

Rabbit

Gene Name URL

CAMK2ACAMK2BCAMK2D

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