BTK Antibody (Phospho-Tyr551)
Product Specifications
CAS Number
9007-83-4
Gene Name
Bruton agammaglobulinemia tyrosine kinase
Gene Aliases
AT, ATK, BPK, XLA, IMD1, AGMX1, IGHD3, PSCTK1
Gene ID
695; 12229
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human Btk around the phosphorylation site of Y551. Location: 490-570aa.
Target
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
80 kDa
Notes
Formerly GWB-6PNW73
Fragment
IgG
Specificity
Phospho-Btk (Tyr551) Polyclonal Antibody detects endogenous levels of Btk protein only when phosphorylated at Y551.
NCBI Gene Symbol
BTK
Host or Source
Rabbit
Gene Name URL
BTK
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