TrpM7 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Transient receptor potential cation channel, subfamily M, member 7

Gene Aliases

CHAK, CHAK1, Channel kinase 1, Channel-kinase 1, Long transient receptor potential channel 7, LTrpC-7, LTRPC7, Transient receptor potential cation channel subfamily M member 7, TRP PLIK, TRPM7, TRPM7_HUMAN

Gene ID

58800

Accession Number

NP_001157797.1

Reactivity

Human, Mouse, Rat

Immunogen

Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7

Target

TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2) .

Clonality

Monoclonal

Clone

S74

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB, IHC, ICC, IF, AM

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol