What is the catalog number for Human CD158e1 Antibody : PE?

The catalog number for Human CD158e1 Antibody : PE is OASB02645-100T.

What sizes are available for Human CD158e1 Antibody : PE?

Human CD158e1 Antibody : PE is available in the following size(s): 100 Tests.

Is Human CD158e1 Antibody : PE in stock?

Human CD158e1 Antibody : PE is currently made to order / not held in immediate stock. Contact us for lead time.

Human CD158e1 Antibody : PE

Product Specifications

CAS Number

9007-83-4

Gene Name

Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

Gene Aliases

KIR, NKB1, NKAT3, NKB1B, NKAT-3, CD158E1, KIR2DL5B, KIR3DL1/S1

Gene ID

3811

Accession Number

NP_001309097.1ï»¿

Reactivity

Human

Immunogen

Human NK clone VL186-1 (CD3-, CD16+, CD56+)

Target

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC) . The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2) . The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

Clonality

Monoclonal

Conjugation

R-PE

Type

Monoclonal Antibody

Applications

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol