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Human CD11b Antibody : FITC

Product Specifications

CAS Number

9007-83-4

Gene Name

Integrin subunit alpha M

Gene Aliases

CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

Gene ID

3684; 397459; 454069; 714832; 101004087; 101866035

Accession Number

NP_000623.2

Reactivity

Human

Immunogen

Rheumatoid synovial cells and human monocytes

Target

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Conjugation

FITC

Type

Monoclonal Antibody

Applications

FC, ICC, IHC-F, WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

Lot specific

Format

Liquid. Phosphate buffered saline containing 0.1% sodium azide

Reconstitution

Store at 2-8C

Specificity

CD11b

NCBI Gene Symbol

ITGAM

Host or Source

Mouse

Protein Name

Integrin alpha-M

Gene Name URL

ITGAMITGAMITGAMITGAMITGAMITGAM

Nucleotide Accession Number

NM_000632.3

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