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Human ZAP-70 Antibody : PE

Product Specifications

CAS Number

9007-83-4

Gene Name

Zeta chain of T cell receptor associated protein kinase 70

Gene Aliases

SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70

Gene ID

7535

Accession Number

NP_001070.2

Reactivity

Human

Immunogen

Human ZAP-70 (a.a. 280-309)

Target

This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

Clonality

Monoclonal

Conjugation

R-PE

Type

Monoclonal Antibody

Applications

FC

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/mL

Format

Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer

Reconstitution

Store at 2-8C

Specificity

ZAP-70

NCBI Gene Symbol

ZAP70

Host or Source

Mouse

Protein Name

Tyrosine-protein kinase ZAP-70

Gene Name URL

ZAP70

Nucleotide Accession Number

NM_001079.3

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