Human ZAP-70 Antibody : AP
Product Specifications
CAS Number
9007-83-4
Gene Name
Zeta chain of T cell receptor associated protein kinase 70
Gene Aliases
SRK, STD, TZK, STCD, IMD48, ADMIO2, ZAP-70
Gene ID
7535
Accession Number
NP_001070.2
Reactivity
Human
Immunogen
Human ZAP-70 (a.a. 280-309)
Target
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Clonality
Monoclonal
Conjugation
AP
Type
Monoclonal Antibody
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Lot specific
Format
Liquid. 50 mM Tris/1 mM MgCl2/50% Glycerol containing 0.1% sodium azide, pH 8.0
Reconstitution
Store at 2-8C
Specificity
ZAP-70
NCBI Gene Symbol
ZAP70
Host or Source
Mouse
Protein Name
Tyrosine-protein kinase ZAP-70
Gene Name URL
ZAP70
Nucleotide Accession Number
NM_001079.3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![6-Isopropoxybenzo[d][1,3]dioxol-5-amine](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
MBS6210668-01 0.1 mL
CD3EAP (DNA-directed RNA Polymerase I Subunit RPA34, A34.5, Antisense to ERCC-1 Protein, ASE-1, CD3-epsilon-associated Protein, CAST, CD3E-associated Protein, RNA Polymerase I-associated Factor PAF49, ASE1, CAST, PAF49) (MaxLight 550)
Sign In for Pricing
View Details MBS6210668-02 5x 0.1 mL
CD3EAP (DNA-directed RNA Polymerase I Subunit RPA34, A34.5, Antisense to ERCC-1 Protein, ASE-1, CD3-epsilon-associated Protein, CAST, CD3E-associated Protein, RNA Polymerase I-associated Factor PAF49, ASE1, CAST, PAF49) (MaxLight 550)
Sign In for Pricing
View Details