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Human Collagen Type I Antibody : Biotin

Product Specifications

CAS Number

9007-83-4

Gene Aliases

OI1, OI2, OI3, OI4, EDSC, CAFYD, EDSARTH1

Gene ID

1277; 1278

Accession Number

NP_000079.2

Reactivity

Mouse, Rat, Bovine, Canine, Chicken, Chinchilla, Elephant, Feline, Guinea Pig, Hamster, Porcine, Rabbit, Sheep, Tree Shrew

Immunogen

Type I collagen

Target

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Source

Pooled antisera from goats hyperimmunized with human type I collagen.

Applications

IHC-P, IHC-F, ICC, EM, FC, WB, IP

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.4 mg/mL

Homology

Human

Format

Liquid. Supplied as 0.2 mg in 0.5 mL (Conc = 0.4 mg/mL) of PBS with 0.1% sodium azide.

Reconstitution

Store at 2-8C

Fragment

IgG

Specificity

Type I Collagen

NCBI Gene Symbol

COL1A1

Host or Source

Goat

Protein Name

Collagen alpha-1 (I) chain

Gene Name URL

COL1A1COL1A2

Nucleotide Accession Number

NM_000088.3

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