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Human IL-25 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Interleukin-25

Gene Aliases

IL17E

Gene ID

64806

Accession Number

NP_073626.1

Reactivity

Human

Immunogen

E. coli-expressed human IL-25

Target

Interleukin-25 (IL-25), also known as interleukin-17E (IL-17E), is a 17 kDa protein and member of the IL-17 cytokine family. This cytokine is secreted by a variety of cells including type 2 helper T cells (Th2), bone marrow-derived mast cells, and alveolar macrophages. On target cells, IL-25 can induce the production of several type 2 cytokines including IL-4, IL-5, and IL-13 and implicates a role for this cytokine in type 2 immune response. Studies have linked this cytokine in promoting airway hyperreactivity, limiting pro-inflammatory cytokine production and chronic intestinal inflammation, and providing protective immunity following intestinal helminth infection.

Clonality

Monoclonal

Clone

SB129e

Conjugation

Unconjugated

Type

Monoclonal Antibody

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/mL

Format

Liquid// Borate buffered saline (pH 8.2), no preservatives or amine-containing buffer salts added

Reconstitution

Store at 2-8C

Molecular Weight

17 kDa

Fragment

IgG2b

Specificity

IL-25

NCBI Gene Symbol

IL25

Host or Source

Mouse

Protein Name

Interleukin-25

Gene Name URL

IL25

Nucleotide Accession Number

NM_022789.3

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