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Human MMP-1 Antibody : Biotin

Product Specifications

CAS Number

9007-83-4

Gene Name

Interstitial collagenase

Gene Aliases

CLG, CLGN

Gene ID

4312; 100009110

Accession Number

NP_002412.1

Reactivity

Human

Immunogen

Recombinant full length MMP-1

Target

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs) . Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD) . Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Clonality

Monoclonal

Clone

SB12e

Conjugation

Biotin

Type

Monoclonal Antibody

Applications

IHC-P, IHC-F, ICC, WB, MP

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/mL

Dilution

1:1,000-1:2,000

Reconstitution

Store at 2-8C

Fragment

IgG2b

Specificity

MMP-1

NCBI Gene Symbol

MMP1

Host or Source

Mouse

Protein Name

Interstitial collagenase

Gene Name URL

MMP1

Nucleotide Accession Number

NM_002421.3

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