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Bcl-2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Apoptosis regulator Bcl-2

Gene Aliases

Bcl-, Bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik

Gene ID

12043; 24224

Accession Number

NP_033871.2

Reactivity

Rat

Immunogen

Murine Bcl-2 peptide (a.a. 61-76)

Target

This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants.

Clonality

Monoclonal

Clone

10C4

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

WB. IP, FC, IHC-F, IHC-P, ICC

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/mL

Dilution

Western Blotting: Purified antibody <= 1 ug/ml

Reconstitution

Store at 2-8C

Notes

Formerly GWB-E1ABD0

Fragment

IgG1

Specificity

Bcl-2

NCBI Gene Symbol

BCL2

Host or Source

Mouse

Protein Name

Apoptosis regulator Bcl-2

Gene Name URL

BCL2

Nucleotide Accession Number

NM_009741.5

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