Bcl-2 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Apoptosis regulator Bcl-2
Gene Aliases
Bcl-, Bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik
Gene ID
12043; 24224
Accession Number
NP_033871.2
Reactivity
Rat
Immunogen
Murine Bcl-2 peptide (a.a. 61-76)
Target
This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants.
Clonality
Monoclonal
Clone
10C4
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
WB. IP, FC, IHC-F, IHC-P, ICC
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/mL
Dilution
Western Blotting: Purified antibody <= 1 ug/ml
Reconstitution
Store at 2-8C
Notes
Formerly GWB-E1ABD0
Fragment
IgG1
Specificity
Bcl-2
NCBI Gene Symbol
BCL2
Host or Source
Mouse
Protein Name
Apoptosis regulator Bcl-2
Gene Name URL
BCL2
Nucleotide Accession Number
NM_009741.5
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