Human Bcl-xL Antibody : PE
Product Specifications
CAS Number
9007-83-4
Gene Name
Bcl-2-like protein 1
Gene Aliases
BCLX, BCL2L, Bcl-X, PPP1R52, BCL-XL/S
Gene ID
598; 12048; 24888; 713035
Accession Number
NP_001182.1
Reactivity
Mouse, Rat, Rhesus
Immunogen
Recombinant human Bcl-xS
Target
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Clonality
Monoclonal
Clone
7B2.5
Conjugation
R-PE
Type
Monoclonal Antibody
Applications
FC
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/mL
Dilution
6 cells
6 cells
6 cells
6 cells
Western Blotting: Purified antibody 6 cells
6 cells
6 cells
Western Blotting: Purified antibody 6 cells
6 cells
Western Blotting: Purified antibody 6 cells
Western Blotting: Purified antibody
Reconstitution
Store at 2-8C
Notes
Formerly GWB-DD749A
Fragment
IgG3
Specificity
Bcl-xL
NCBI Gene Symbol
BCL2L1
Host or Source
Mouse
Protein Name
Bcl-2-like protein 1
Gene Name URL
BCL2L1
Nucleotide Accession Number
NM_001191.3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
