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Human CD51 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Integrin alpha-V

Gene Aliases

CD51, MSK8, VNRA, VTNR

Gene ID

3685; 103217487; 100008956; 281875

Accession Number

NP_001138471.1

Reactivity

Human

Immunogen

Cell suspension containing osteoclasts from osteoclastomas

Target

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Clonality

Monoclonal

Clone

13C2

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

FC, IHC-F, ICC, IP, BL

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/mL

Format

Liquid Borate buffered saline (pH 8.2), no preservatives or amine-containing buffer salts added

Reconstitution

Store at 2-8C

Notes

Formerly GWB-E7DCA1

Fragment

IgG1

Specificity

CD51

NCBI Gene Symbol

ITGAV

Host or Source

Mouse

Protein Name

Integrin alpha-V

Gene Name URL

ITGAV

Nucleotide Accession Number

NM_001144999.2

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