Human CD51 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Integrin alpha-V
Gene Aliases
CD51, MSK8, VNRA, VTNR
Gene ID
3685; 103217487; 100008956; 281875
Accession Number
NP_001138471.1
Reactivity
Human
Immunogen
Cell suspension containing osteoclasts from osteoclastomas
Target
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Clonality
Monoclonal
Clone
13C2
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
FC, IHC-F, ICC, IP, BL
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/mL
Format
Liquid Borate buffered saline (pH 8.2), no preservatives or amine-containing buffer salts added
Reconstitution
Store at 2-8C
Notes
Formerly GWB-E7DCA1
Fragment
IgG1
Specificity
CD51
NCBI Gene Symbol
ITGAV
Host or Source
Mouse
Protein Name
Integrin alpha-V
Gene Name URL
ITGAV
Nucleotide Accession Number
NM_001144999.2
Frequently Asked Questions
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