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Human CD11b/Mac-1a Antibody : SPRD

Product Specifications

CAS Number

9007-83-4

Gene Name

Integrin alpha-M

Gene Aliases

CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6

Gene ID

3684; 397459; 714832; 101866035; 454069; 101004087

Accession Number

NP_000623.2

Reactivity

Human

Immunogen

Rheumatoid synovial cells and human monocytes

Target

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Clone

ICRF44

Conjugation

Spectral Red®

Type

Monoclonal Antibody

Applications

FC

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

Lot specific

Dilution

6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells66666

Reconstitution

Store at 2-8C

Fragment

IgG1

Specificity

CD11b

NCBI Gene Symbol

ITGAM

Host or Source

Mouse

Protein Name

Integrin alpha-M

Gene Name URL

ITGAM

Nucleotide Accession Number

NM_000632.3

Frequently Asked Questions

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