Human CD11b/Mac-1a Antibody : APC
Product Specifications
CAS Number
9007-83-4
Gene Name
Integrin alpha-M
Gene Aliases
CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
Gene ID
3684; 397459; 714832; 101866035; 454069; 101004087
Accession Number
NP_000623.2
Reactivity
Human
Immunogen
Rheumatoid synovial cells and human monocytes
Target
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3') . The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality
Monoclonal
Clone
ICRF44
Conjugation
APC
Type
Monoclonal Antibody
Applications
FC
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
Lot specific
Dilution
6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells66666
Reconstitution
Store at 2-8C
Fragment
IgG1
Specificity
CD11b
NCBI Gene Symbol
ITGAM
Host or Source
Mouse
Protein Name
Integrin alpha-M
Gene Name URL
ITGAM
Nucleotide Accession Number
NM_000632.3
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